Indian State of Tripura on the north, Khagrachhari Sadar upazila on the south, Dighinala upazila on the east and Matiranga upazila on the west.

Panchhari thana was turned into an upazila in 1983. The upazila consists of 4 union parishads, 7 mouzas and 57 villages.

Panchhari Upazila is located in Khagrachhari District. Upazilla(s)/Thana(s) in Khagrachhari are Dighinala Upazila, Khagrachhari Sadar Upazila, Lakshmichhari Upazila, Mahalchhari Upazila, Manikchhari Upazila, Matiranga Upazila, Panchhari Upazila, Ramgarh Upazila.